- Robert Allen, Wabash '57, Former Chairman, AT&T
- William W. Allen, Oklahoma State '56, CEO Phillips Petroleum
- Neil Armstrong, Purdue '55, Astronaut, First man on the moon
- James A. Baker, Texas '57, Former Secretary of State
- William B. Bankhead, Alabama 1893, Speaker of the U.S. House of Representatives 1934-41
- Gary Bender, Wichita '62, Television Sportscaster
- Dirk Benedict, Whitman '67, Actor
- Bill Bixby, California '56, Actor
- Rich Brooks, Oregon State '63, Football Coach, Kentucky
- Chris Cagle, Northwest Missouri State '90, Country Singer
- Ron Cey, Washington State '70, Former L.A. Dodger
- Dabney Coleman, Texas '53, Actor
- Barber Conable, Cornell '43, Former President of the World Bank
- Tim Conway, Bowling Green '56, Actor, Comedian
- John Dasburg, University of Miami '65, CEO, Burger King
- Mark DeCarlo, Drake '84, Actor & TV Host
- Greg Dell'Omo, Pittsburgh '77, President, Robert Morris University
- George Eads, Texas Tech '89, Actor
- Roger Ebert, Illinois '64, Film Critic, Columnist
- Morgan Ensberg, Southern California '98, Baseball Player
- Weeb Ewbank, Miami University '28, NFL Coach
- George M. C. Fisher, Illinois '62, CEO, Eastman Kodak
- Ralph Friedgen, Maryland '70, Maryland Football Coach
- Lou Gehrig, Columbia University '25, First Baseman, New York Yankees
- Jack Ham, Penn State '71, NFL Hall of Fame
- Tom Harmon, Michigan '41, 1940 Heisman-winner
- Benjamin Harrison, Miami University 1853, Former U.S. President
- Mark Hurd, Baylor '79, Former CEO, Hewlett-Packard
- F. Ross Johnson, Manitoba '52, Former CEO of RJR Nabisco
- Harry Kalas, Iowa '59, Hall of Fame MLB Broadcaster and Voice of NFL Films
- Hank Ketchum, Washington '41, Cartoonist, "Dennis the Menace"
- Francis D. Lyon, UCLA '28, Academy Award Winning Director
- J. Willard Marriott, Utah '25, Founder, Marriott Hotels
- Michael V. Martin, Minnesota State '69, Chancellor, LSU
- Michael McDonald, Southern Cal '86, Actor
- James McLamore, Cornell '47, Founder, Burger King
- Jason McManus, Davidson '56, Editor-in-Chief, Time Magazine
- Don Meredith, Southern Methodist '60
- James B. Milliken, Nebraska '79, President, University of Nebraska
- F. Story Musgrave, Syracuse '58, Astronaut
- Sam Nunn, Georgia Tech '60, Former U.S. Senator
- Jim Otto, Miami (Fl.) '60, NFL Hall of Fame
- Billy Payne, Georgia '69, President, '96 Atlanta Olympic Games Organizing Committee
- Burt Reynolds, Florida Sate '57, Actor
- Grantland Rice, Vanderbilt 1901, Fames Sportswriter
- Bob Schieffer, Texas Christian '59, CBS News Anchor
- Detlef Schrempf, Washington '84, NBA All-Star
- C.J. Silas, Georgia Tech '53, Former CEO, Phillips Petroleum
- John Smale, Miami '49, Former CEO, Procter & Gamble
- Roger Smith, Michigan '52, Former Chairman of GM
- Adlai Stevenson, Centre 1860, U.S. Vice President 1893-97
- Steve Tasker, Northwestern '84, NFL All-Pro
- Mike Timlin, Southwestern '88, MLB Player
- John Tyson, Arkansas '75, Chairman, Tyson Foods
- Phil Walden, Mercer '62, President, Capricorn Record
- Doak Walker, Southern Methodist '50, NFL Hall of Fame
- Wes Welker, Texas Tech '04, NFL Wide Receiver
- William Weiss, Pennsylvania State '51, CEO Ameritech Corp.
- Gary Williams, Maryland '68, Maryland Basketball Coach
- Gary Wilson, Duke '62, Former Chairman, Northwest Airlines
- Ralph Wilson, Virginia '40, Owner, Buffalo Bills
- Trey Wingo, Baylor '85, ESPN Sports Anchor
- Robert E. Witt, Alabama '79, President, University of Alabama
- Frank Lloyd
Wright, Wisconsin 1889, Architect